In this new configuration, intracellular loop 3 (ICL3) and transmembrane helix 6 (TM6) of the receptor are oriented toward the N-terminal domain of the arrestin, making it possible for GPCRs that lack the C-terminal tail to couple Arr2 through their ICL3. View Eric Xu’s profile on LinkedIn, the world's largest professional community. Following a postdoctoral fellowship with Carl Pabo at MIT, he moved to GlaxoWellcome in 1996 as a Research Investigator I. G-protein coupled receptors 5 VARI/SIMM Center, Center for Structure and Function of Drug Targets, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. Name must be less than 100 characters 4 Center for Cancer and Cell Biology, Van Andel Research Institute, 333 Bostwick Ave. Research of his group covers structure and drug discovery of nuclear hormone receptors, hepatocyte growth factor and its receptor Met tyrosine kinase, G-protein coupled receptors, and plant hormones.Recognize this scientist’s Expertise for their contribution in your researchYin W, Mao C, Luan X, Shen DD, Shen Q, Su H, Wang X, Zhou F, Zhao W, Gao M, Chang S, Xie YC, Tian G, Jiang HW, Tao SC, Shen J, Jiang Y, Jiang H, Xu Y, Zhang S, Zhang Y, Xu HE. Epub 2014 May 27.Handb Exp Pharmacol. Eric (Huaqiang) Xu. XING – For a better working life Das Profilbild siehst Du, wenn Du Dich bei XING einloggst. plant hormones He returned to China in 2019 as a full-time researcher. 2020 Feb 20;180(4):645-654.e13. Cell. Clipboard, Search History, and several other advanced features are temporarily unavailable. Dr. Xu earned his bachelor and master degrees at Tsinghua University from 1981 to 1988. Current city. 2013;521:91-108. doi: 10.1016/B978-0-12-391862-8.00005-3.Stadler AM, Granzin J, Cousin A, Batra-Safferling R.Sci Rep. 2020 Jul 2;10(1):10938. doi: 10.1038/s41598-020-67944-0.Lee Y, Warne T, Nehmé R, Pandey S, Dwivedi-Agnihotri H, Chaturvedi M, Edwards PC, García-Nafría J, Leslie AGW, Shukla AK, Tate CG.Nature. Dr. Xu joined VARI as a Senior Scientific Investigator in July 2002 and became a Distinguished Investigator/Professor in March 2007. 471 comments View Eric Xu’s profile on LinkedIn, the world's largest professional community. While arrestins 1 and 4 are visual arrestins dedicated to rhodopsin, arrestins 2 and 3 (Arr2 and Arr3) are β-arrestins known to regulate many nonvisual GPCRs. Epub 2018 Aug 22.Zhou XE, He Y, de Waal PW, Gao X, Kang Y, Van Eps N, Yin Y, Pal K, Goswami D, White TA, Barty A, Latorraca NR, Chapman HN, Hubbell WL, Dror RO, Stevens RC, Cherezov V, Gurevich VV, Griffin PR, Ernst OP, Melcher K, Xu HE. N.E., Grand Rapids, MI 49503, USA. 2014 Jul 25;289(30):20991-1002. doi: 10.1074/jbc.M114.560680. Epub 2020 Jan 30.Zhao LH, Ma S, Sutkeviciute I, Shen DD, Zhou XE, de Waal PW, Li CY, Kang Y, Clark LJ, Jean-Alphonse FG, White AD, Yang D1, Dai A, Cai X, Chen J, Li C, Jiang Y, Watanabe T, Gardella TJ, Melcher K, Wang MW, Vilardaga JP, Xu HE, Zhang Y. Met tyrosine kinase He is a graduate of Shanghai University of Finance & Economics and holds a Master of Finance from the University of Manchester (UK) School of Business and UMIST, respectively.
Eric Xu is on Facebook. He is a graduate of Shanghai University of Finance & Economics and holds a Master of Finance from the University of Manchester (UK) School of Business and UMIST, respectively.Eric Xu joined GGV Capital in 2017 as a Managing Partner, focusing on consumer/new retail and social/internet investments.
Prior to his career in venture capital, Eric was an investment banker at CLSA and its JV in China. 2006 Feb 3;281(5):2932-8. doi: 10.1074/jbc.M508074200. 2014;219:173-86. doi: 10.1007/978-3-642-41199-1_9.Methods Enzymol. Basic XING membership is free and always will be.
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drug discovery View Eric Xu’s profile on LinkedIn, the world's largest professional community. 2017 Jul 27;170(3):457-469.e13. Epub 2020 Jun 5.Gomes I, Sierra S, Lueptow L, Gupta A, Gouty S, Margolis EB, Cox BM, Devi LA.Proc Natl Acad Sci U S A. Shanghai, China. Science. XING complies with German data protection law. In 2013, he helped to establish and serve as the founding Director of the Key Laboratory of Receptor Research of Chinese Academy of Sciences. Log In. Eric has 5 jobs listed on their profile. Molecular dynamics simulation and crosslinking data further support the assembly of the Arr2‒NTSR1 complex. Shanghai Institute of Materia Medica (SIMM) is one of the most premier Institutes on drug discovery and development in Chinese Academy of Sciences. 4745 posts | Join the largest online business network in D-A-CH. In July 2010, Dr. Xu established and served as the distinguished Director of the VARI-SIMM Center for Drug Discovery at Shanghai Institute of Materia of Chinese Academy of Sciences. Full-time employee in Shanghai This site needs JavaScript to work properly. Find your dream job, add valuable contacts, share expertise, and achieve greater success thanks to XING. Eric has 4 jobs listed on their profile. enzyme structure XING is Germany's largest online business network: Find your dream job, add valuable contacts, share expertise, and achieve greater success thanks to XING.
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